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Cancer cells have a lot of other things that are really wrong with them, and we should never forget that these are cells that have become deaf to all the signals that the body sends out, such as you can multiply a certain amount, you can be in a certain place in the body, where to stay, where to move, and so on.
~ Elizabeth Blackburn
Amount
Become
Body
Cancer
Cells
Certain
Deaf
Forget
Lot
Move
Multiply
Never
Never Forget
Other
Out
Place
Really
Sends
Should
Signals
Stay
Them
Things
Where
Wrong
You
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Cancer cells have had so many other things go wrong with them, genetic, non-genetic changes, that those cells, one of the things they then get selected for is that they have lots of telomerase because now the telomeres in those cells get maintained.
~ Elizabeth Blackburn
Because
Cancer
Cells
Changes
Genetic
Get
Go
Had
Lots
Maintained
Many
Now
One Of The Things
Other
Selected
Them
Then
Things
Those
Wrong
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Challenges in medicine are moving from 'Treat the symptoms after the house is on fire' to 'Can we preserve the house intact?'
~ Elizabeth Blackburn
After
Challenges
Fire
House
Intact
Medicine
Moving
Preserve
Symptoms
Treat
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Checking your telomere length is a bit like weighing yourself: you get this single number which depends on a lot of factors. Telomere length gives a sense of your underlying health.
~ Elizabeth Blackburn
Bit
Checking
Depends
Factors
Get
Gives
Health
Length
Like
Lot
Number
Sense
Single
Underlying
Weighing
Which
You
Your
Yourself
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Exercise mitigates the effects of stress - and stress, we know, shortens telomeres. In fact, early studies indicate that stress reduction techniques like meditation help people maintain the length of their telomeres.
~ Elizabeth Blackburn
Early
Effects
Exercise
Fact
Help
Help People
In Fact
Indicate
Know
Length
Like
Maintain
Meditation
People
Reduction
Stress
Studies
Techniques
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For me, arguably the story of telomeres and telomerase began thousands of years ago, in the cornfields of the Maya highlands of Central America.
~ Elizabeth Blackburn
America
Arguably
Began
Central
Central America
Me
Story
Thousands
Thousands Of Years
Years
Years Ago
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Generally, we try to have a situation where the person is healthy, so you're not confounded by disease. So, that means that healthy individuals are donating their blood samples for the studies.
~ Elizabeth Blackburn
Blood
Confounded
Disease
Generally
Healthy
Individuals
Means
Person
Samples
Situation
Studies
Try
Where
You
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I chose biochemistry as my major and graduated after 4 years with an Honours degree in Biochemistry. During that time, I had come to love biochemistry research, although I was just getting my feet wet in laboratory research.
~ Elizabeth Blackburn
After
Although
Biochemistry
Chose
Come
Degree
Feet
Getting
Graduated
Had
Honours
Just
Laboratory
Love
Major
Research
Time
To Love
Wet
Years
design
copy
I decided I wanted to go to Cambridge, and then I got introduced to Fred Sanger. I was very conscientious, and I asked him when I first got there if I should start reading up on things. But he said, 'No, I think you can just start these experiments,' so I plunged right in.
~ Elizabeth Blackburn
Asked
Cambridge
Conscientious
Decided
Experiments
First
Fred
Go
Got
He
Him
I Think
Introduced
Just
Reading
Right
Said
Should
Start
Then
Things
Think
Up
Very
Wanted
You
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I spent my first 4 years living in the tiny town of Snug, by the sea near Hobart. Curious about animals, I would pick up ants in our backyard and jellyfish on the beach.
~ Elizabeth Blackburn
About
Animals
Ants
Backyard
Beach
Curious
First
Living
Near
Our
Pick
Sea
Spent
Tiny
Town
Up
Would
Years
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I was born in the small city of Hobart in Tasmania, Australia, in 1948. My parents were family physicians. My grandfather and great grandfather on my mother's side were geologists.
~ Elizabeth Blackburn
Australia
Born
City
Family
Grandfather
Great
Great-Grandfather
I Was Born
Mother
Parents
Physicians
Side
Small
Were
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I was using very unconventional methods to sequence the telemetric DNA, originally.
~ Elizabeth Blackburn
DNA
Methods
Originally
Sequence
Unconventional
Using
Very
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I'm pretty good about getting some exercise every day - well, most days. The secret for me was to put the elliptical in front of the TV.
~ Elizabeth Blackburn
About
Day
Days
Every
Every Day
Exercise
Front
Getting
Good
Me
Most
Pretty
Pretty Good
Put
Secret
Some
TV
Well
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I've only actively promoted what we always hope is good science.
~ Elizabeth Blackburn
Actively
Always
Good
Hope
Only
Promoted
Science
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If a test showed you had telomere shortening, it would be a red flag suggesting you should take a look at possible risk factors.
~ Elizabeth Blackburn
Factors
Flag
Had
Look
Possible
Red
Risk
Should
Suggesting
Take
Test
Would
Would-Be
You
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If we think of our chromosomes - they carry our genetic material - as being like shoelaces, I work on the plastic tips at the end that protect them.
~ Elizabeth Blackburn
Being
Carry
End
Genetic
Like
Material
Our
Plastic
Protect
Them
Think
Tips
Work
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In 2004, results from a study that I worked on with colleagues at the University of California, San Francisco, linked chronic stress to shortening of telomeres.
~ Elizabeth Blackburn
California
Chronic
Colleagues
Francisco
Linked
Results
San
San Francisco
Stress
Study
University
University Of California
Worked
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In humans, the thing is that as we mature, our telomeres slowly wear down. So the question has always been: 'Did that matter?' Well, more and more, it seems like it matters.
~ Elizabeth Blackburn
Always
Been
Did
Down
Humans
Like
Matter
Matters
Mature
More
More And More
Our
Question
Seems
Slowly
Thing
Wear
Well
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In my early work, our molecular views of telomeres were first focused on the DNA.
~ Elizabeth Blackburn
DNA
Early
Early Work
First
Focused
Molecular
Our
Views
Were
Work
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In my lab, we're finding that psychological stress actually ages cells, which can be seen when you measure the wearing down of the tips of the chromosomes, those telomeres.
~ Elizabeth Blackburn
Actually
Ages
Cells
Down
Finding
Lab
Measure
Psychological
Seen
Stress
Those
Tips
Wearing
Which
You
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