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If the aging process is controlled in a similar way in worms and humans, then we can use what we learn about worms to speed our study of higher organisms.
~ Cynthia Kenyon
About
Aging
Controlled
Higher
Humans
Learn
Organisms
Our
Process
Similar
Speed
Study
Then
Use
Way
Worms
design
copy
Imagine that: If you could change one of the genes in an experiment, an aging gene, maybe you could slow down aging and extend lifespan.
~ Cynthia Kenyon
Aging
Change
Could
Down
Experiment
Extend
Gene
Genes
Imagine
Maybe
Slow
You
design
copy
In principle, if you understood the mechanisms of keeping things repaired, you could keep things going indefinitely.
~ Cynthia Kenyon
Could
Going
Indefinitely
Keep
Keeping
Mechanisms
Principle
Things
Understood
You
design
copy
In the early '90s, we discovered mutations that could double the normal life span of worms.
~ Cynthia Kenyon
Could
Discovered
Double
Early
Life
Life Span
Mutations
Normal
Normal Life
Span
Worms
design
copy
It is unlikely that changes in telomeres are influencing the lifespan of the worm. That is because telomeres only shorten when cells divide. Most of the cells of the worm stop dividing when the worm becomes an adult.
~ Cynthia Kenyon
Adult
Because
Becomes
Cells
Changes
Divide
Dividing
Influencing
Most
Only
Shorten
Stop
Unlikely
Worm
design
copy
It was like stepping on to an escalator; I could do anything. I was just made for science.
~ Cynthia Kenyon
Anything
Could
Escalator
Just
Like
Made
Science
Stepping
design
copy
It's like, say, if you were a dog. You notice that you're getting old, and you look at your human and you think, 'Why isn't this human getting old?'... But now we're the human looking out and imagining a different human.
~ Cynthia Kenyon
Different
Dog
Getting
Getting Old
Human
Imagining
Like
Look
Looking
Notice
Now
Old
Out
Say
Think
Were
Why
You
Your
design
copy
It's possible that we could change a human gene and double our life span. I don't know if that's true, but we can't rule that out.
~ Cynthia Kenyon
Change
Could
Double
Gene
Human
Know
Life
Life Span
Our
Out
Possible
Rule
Span
True
design
copy
Just living longer and being sick is the worst. But the idea that you could have fewer diseases, and just have a healthy life and then turn out the lights, that's a good vision to have. And I think what we know about some of these pathways suggests that might be possible.
~ Cynthia Kenyon
About
Being
Could
Diseases
Fewer
Good
Healthy
I Think
Idea
Just
Just Living
Know
Life
Lights
Living
Longer
Might
Out
Possible
Sick
Some
Then
Think
Turn
Vision
Worst
You
design
copy
Life's too short to not be around nice people.
~ Cynthia Kenyon
Around
Life
Nice
Nice People
People
Short
Too
design
copy
Maybe one day we will be able to take a pill that keeps us young and healthy much longer. I believe in my heart that this will happen.
~ Cynthia Kenyon
Able
Believe
Day
Happen
Healthy
Heart
I Believe
I Believe In
Keeps
Longer
Maybe
Much
One Day
Pill
Take
Us
Will
Young
design
copy
One thing that's likely: How you look as you age is hereditary. Some of my family members, for example, look younger than their real age. And people have mistaken me for 30, even 25.
~ Cynthia Kenyon
Age
Even
Example
Family
Family Members
For Example
Hereditary
How
Likely
Look
Me
Members
Mistaken
One Thing
People
Real
Some
Than
Thing
You
Younger
design
copy
Perhaps genes did regulate the aging process. Perhaps different organisms had different life spans because a universal regulatory 'clock' was set to run at different speeds in different species.
~ Cynthia Kenyon
Aging
Because
Clock
Did
Different
Different Life
Genes
Had
Life
Organisms
Perhaps
Process
Regulate
Regulatory
Run
Set
Spans
Species
Speeds
Universal
design
copy
Sugar is the new tobacco.
~ Cynthia Kenyon
New
Sugar
Tobacco
design
copy
The hope is that if we can increase youthfulness, we can postpone age-related diseases.
~ Cynthia Kenyon
Diseases
Hope
Increase
Postpone
design
copy
The idea that ageing was subject to control was completely unexpected.
~ Cynthia Kenyon
Ageing
Control
Idea
Subject
Unexpected
design
copy
The public is absolutely fascinated by aging. They don't want to get old. And you can see - read Shakespeare. Read the sonnets. They're all about aging.
~ Cynthia Kenyon
About
Absolutely
Aging
Fascinated
Get
Old
Public
Read
See
Shakespeare
Want
You
design
copy
There are lots of different strategies that an animal can use to survive. What a worm does is try to convert food into worms as soon as possible. In three days a single worm produces 300 progeny. So why put your resources into developing if you can make a brand-new worm in no time at all?
~ Cynthia Kenyon
Animal
Convert
Days
Developing
Different
Does
Food
Lots
Make
No Time
Possible
Produces
Put
Resources
Single
Soon
Strategies
Survive
Three
Time
To Survive
Try
Use
Why
Worm
Worms
You
Your
design
copy
We are trying to find drugs, small molecules, that people could take to make them disease-resistant, more youthful and healthy. Eventually we will find them.
~ Cynthia Kenyon
Could
Eventually
Find
Healthy
Make
Molecules
More
People
Small
Take
Them
Trying
Will
Youthful
design
copy
With science it's very important not to go down the wrong path, but the wrong path in science is a path you go down where everything you learn is already known. So you need to steer around the obvious.
~ Cynthia Kenyon
Around
Down
Everything
Go
Important
Known
Learn
Need
Obvious
Path
Science
Steer
Very
Where
Wrong
You
design
copy
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