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Elizabeth Blackburn Quotes
If a test showed you had telomere shortening, it would be a red flag suggesting you should take a look at possible risk factors.
~ Elizabeth Blackburn
Factors
Flag
Had
Look
Possible
Red
Risk
Should
Suggesting
Take
Test
Would
Would-Be
You
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If we think of our chromosomes - they carry our genetic material - as being like shoelaces, I work on the plastic tips at the end that protect them.
~ Elizabeth Blackburn
Being
Carry
End
Genetic
Like
Material
Our
Plastic
Protect
Them
Think
Tips
Work
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In 2004, results from a study that I worked on with colleagues at the University of California, San Francisco, linked chronic stress to shortening of telomeres.
~ Elizabeth Blackburn
California
Chronic
Colleagues
Francisco
Linked
Results
San
San Francisco
Stress
Study
University
University Of California
Worked
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In humans, the thing is that as we mature, our telomeres slowly wear down. So the question has always been: 'Did that matter?' Well, more and more, it seems like it matters.
~ Elizabeth Blackburn
Always
Been
Did
Down
Humans
Like
Matter
Matters
Mature
More
More And More
Our
Question
Seems
Slowly
Thing
Wear
Well
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In my early work, our molecular views of telomeres were first focused on the DNA.
~ Elizabeth Blackburn
DNA
Early
Early Work
First
Focused
Molecular
Our
Views
Were
Work
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In my lab, we're finding that psychological stress actually ages cells, which can be seen when you measure the wearing down of the tips of the chromosomes, those telomeres.
~ Elizabeth Blackburn
Actually
Ages
Cells
Down
Finding
Lab
Measure
Psychological
Seen
Stress
Those
Tips
Wearing
Which
You
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In the 1970s, I did a Ph.D. with Fred Sanger in Cambridge who was in the process of inventing ways to map what's inside DNA. He later won the Nobel Prize.
~ Elizabeth Blackburn
1970s
Cambridge
Did
DNA
Fred
He
Inside
Inventing
Later
Map
Nobel
Nobel Prize
Prize
Process
Ways
Who
Won
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Medicine has been successful by treating diseases in a very specific way once the damage is done. But telomere length integrates a lot of factors together and gives you an overall picture of risk for what is now emerging as a lot of diseases that tend to occur together, such as diabetes and heart disease.
~ Elizabeth Blackburn
Been
Damage
Diabetes
Disease
Diseases
Done
Emerging
Factors
Gives
Has-Been
Heart
Heart Disease
Length
Lot
Medicine
Now
Occur
Once
Overall
Picture
Risk
Specific
Successful
Tend
Together
Treating
Very
Way
You
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No one ever said, 'Be a doctor.' But because so many members of my extended family - aunts, uncles - were doctors, there was this expectation that I'd probably be a physician.
~ Elizabeth Blackburn
Aunts
Because
Doctor
Doctors
Ever
Expectation
Extended
Extended Family
Family
Many
Members
No-One
Physician
Said
Uncles
Were
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Observational studies show that exercise, nutritional supplements and reducing psychological stress can help. Chronic high stress and smoking can lead to accelerated telomere shortening.
~ Elizabeth Blackburn
Accelerate
Chronic
Exercise
Help
High
Lead
Psychological
Reducing
Show
Smoking
Stress
Studies
Supplements
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One characteristic aspect of ageing is the increased susceptibility to disease, particularly age-related diseases such as cardiovascular diseases and cancer.
~ Elizabeth Blackburn
Ageing
Aspect
Cancer
Cardiovascular
Characteristic
Disease
Diseases
Increased
Particularly
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Perhaps arising from a fascination with animals, biology seemed the most interesting of sciences to me as a child.
~ Elizabeth Blackburn
Animals
Arising
Biology
Child
Fascination
Interesting
Me
Most
Perhaps
Sciences
Seemed
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Researchers have found that the brain definitely sends nerves directly to organs of the immune system and not just to the heart and the lower gut. In that way, too, the brain is influencing the body.
~ Elizabeth Blackburn
Body
Brain
Definitely
Directly
Found
Gut
Heart
Immune
Influencing
Just
Lower
Nerves
Organs
Researchers
Sends
System
Too
Way
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Studying organisms at a molecular level was totally compelling because it was moving from being a naturalist, which was the 19th-century kind of science, to being very focused and really getting to the heart of these molecules.
~ Elizabeth Blackburn
Because
Being
Compelling
Focused
Getting
Heart
Kind
Level
Molecular
Molecules
Moving
Naturalist
Organisms
Really
Science
Studying
Totally
Very
Which
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Telomeres are the protective caps at the ends of chromosomes in cells. Chromosomes carry the genetic information. Telomeres are buffers. They are like the tips of shoelaces. If you lose the tips, the ends start fraying.
~ Elizabeth Blackburn
Caps
Carry
Cells
Ends
Genetic
Information
Like
Lose
Protective
Start
Tips
You
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The conservative statement is that telomere length is a biomarker, but it's probably not passive. There are some very intimate relationships between things such as molecular markers for inflammation and telomere health.
~ Elizabeth Blackburn
Between
Conservative
Health
Intimate
Length
Molecular
Passive
Relationships
Some
Statement
Things
Very
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The goal is to learn more about telomere length and other markers of ageing, how best to measure these markers, how they are related to health and lifestyle, and how people respond to learning their own telomere length results.
~ Elizabeth Blackburn
About
Ageing
Best
Goal
Health
How
Learn
Learning
Length
Lifestyle
Measure
More
Other
Own
People
Related
Respond
Results
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The most dangerous cancer cells are actually the ones that are more like stem cells, which have this ability to produce themselves over and over again. More and more cancer biologists say stem-cell-like cells in cancers are the most dangerous.
~ Elizabeth Blackburn
Ability
Actually
Again
Biologists
Cancer
Cells
Dangerous
Like
More
More And More
Most
Over
Produce
Say
Stem
Stem Cells
Themselves
Which
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This enzyme, called telomerase, slows the rate at which telomeres degrade, and research indicates that healthy people with longer telomeres have less risk of developing the common illnesses of aging - like heart disease, diabetes, and cancer, which are three big killers today.
~ Elizabeth Blackburn
Aging
Big
Cancer
Common
Degrade
Developing
Diabetes
Disease
Healthy
Healthy People
Heart
Heart Disease
Illnesses
Less
Like
Longer
People
Rate
Research
Risk
Three
Today
Which
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Tracing the beginnings of the interwoven stories of science can be arbitrary, as beginnings are so often lost in the mists of time.
~ Elizabeth Blackburn
Arbitrary
Beginnings
Interwoven
Lost
Often
Science
Stories
Time
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AuthorName
Elizabeth Blackburn
Profession
Scientist
BirthDate
26 November, 1948
Country
Australia
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